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- MBS Monoclonals
- CA15-3 Antibody-Biotin
Product short description
Price:
442 EUR
Size:
100ug
Catalog no.:
GEN850041
Product detailed description
Gene name synonims
N/A
Other gene names
N/A
Clone
N/A
Other names
N/A
Immunoglobulin isotype
IgG1
Gene name
CA15-3
Also known as
CA15-3
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Concentration
0.1mg/0.1ml
Conjugation
Biotinylated
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Purification method
>98% pure. Protein A chromatography
Tested applications:
ELISA (EIA), Immunoprecipitation (IP), ICH, Western Blot (WB)
Form/Appearance
MAb to Carbohydrate Antigen CA15-3-BIOTIN in 150mM NaCl 10mM Tris pH7.4
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
Short-term Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Long term For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Avoid multiple freeze/thaw cycles.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
Specificity and cross-reactivity
Specific for the tandem repeat of the MUC-1 core. Recognizes the hexapeptide (TRPAPG). The MUC-1 mucin (Cancer Antigen CA15-3) is secreted from tumor cells. The apo-protein of the MUC-1 mucin contains a transmembrane domain, a cytoplasmic domain, and an extracellular carbohydrate rich domain. The extracellular domain is characterized by polymorphism with respect to the number of a 20 amino acid tandem repeat (VNTR polymorphism).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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