PDGF Receptor alpha/beta, phosphorylated (Tyr849/Tyr857)

575 EUR

100ul

GEN601271

N/A

N/A

N/A

N/A

N/A

IgG

8A26

Antibodies

Monoclonal

Supernatant

Human (Homo sapiens)

Mnoclonal antibodies

PDGF Receptor alpha/beta

Rabbit (Oryctolagus cuniculus)

ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)

Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, < 0.02% sodium azide, 50% glycerol.

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 

Recognizes endogenous levels of human PDGF receptor alpha and beta at ~190kD only when phosphorylated on Tyr849 of PDGFR alpha and Tyr857 of PDGFR beta. May crossreact with other activated tyrosine kinases. Species Crossreactivity: Mouse, rat; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

The PDGF Receptor alpha/beta, phosphorylated (Tyr849/Tyr857) is a α- or alpha protein sometimes glycoprotein present in blood.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.