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- IgM (Immunoglobulin Mu Heavy Chain)
Product short description
Price:
                                                                                    354 EUR
                                                                            
                                Size:
                                        100ug
                                    
                                Catalog no.:
                                        GEN438139
                                    
                                Product detailed description
Additional isotype
                                        IgM
                                    
                                Gene name synonims
                                        N/A
                                    
                                Purification method
                                        N/A
                                    
                                Form/Appearance
                                        N/A
                                    
                                Concentration
                                        N/A
                                    
                                Also known as
                                        IgM
                                    
                                Gene name
                                        IGHM
                                    
                                Clone
                                        IM260
                                    
                                Clonality
                                        Monoclonal
                                    
                                Category
                                        Antibodies
                                    
                                Immunoglobulin isotype
                                        IgG1, kappa
                                    
                                Subcategory
                                        Mnoclonal antibodies
                                    
                                Host organism
                                        Mouse (Mus musculus)
                                    
                                Other gene names
                                        IGHM; IGHM; MU; VH; AGM1; N/A
                                    
                                Other names
                                        Ig mu chain C region, partial; Ig mu chain C region; N/A; immunoglobulin heavy constant mu; N/A
                                    
                                Tested applications:
                                        ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
                                    
                                Storage and shipping
                                        Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
                                    
                                Species reactivity
                                        Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
                                    
                                Properties
                                        Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to an antigen
                                    
                                Specificity and cross-reactivity
                                        Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
                                    
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