Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438253
Product detailed description
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Gene name synonims
N/A
Clone
SPM282
Gene name
MAGEA1
Also known as
MAGE-1
Clonality
Monoclonal
Category
Antibodies
Immunoglobulin isotype
IgG1, kappa
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Other gene names
MAGEA1; MAGEA1; CT1.1; MAGE1; MAGE1; MAGE1A; CT1.1
Tested applications:
ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens), Rat (Rattus norvegicus), Dog.; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
melanoma-associated antigen 1; Melanoma-associated antigen 1; melanoma-associated antigen 1; antigen MZ2-E; MAGE-1 antigen; melanoma antigen MAGE-1; cancer/testis antigen 1.1; melanoma antigen family A 1; melanoma-associated antigen MZ2-E; cancer/testis antigen family 1, member 1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E); Antigen MZ2-E; Cancer/testis antigen 1.1; CT1.1; MAGE-1 antigen
Specificity and cross-reactivity
Recognizes a protein of 42-46kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.