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- MBS Monoclonals
- Lambda Light Chain
Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438288
Product detailed description
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Gene name
IGL
Gene name synonims
N/A
Other gene names
N/A
Clone
HP6054
Category
Antibodies
Clonality
Monoclonal
Immunoglobulin isotype
IgG2a, kappa
Also known as
Lambda Light Chain
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Other names
Ig lambda chain V-I region NEW, partial; Ig lambda chain V-I region NEW; N/A; N/A; N/A
Tested applications:
ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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