PLGF

354 EUR

100ug

GEN438326

PGF

N/A

N/A

N/A

N/A

PLGF

PLGF94

Monoclonal

Antibodies

IgG1, kappa

Mouse (Mus musculus)

Mnoclonal antibodies

ELISA (EIA), Functional Studies

PGF; PGF; PGFL; PLGF; PlGF-2; D12S1900; SHGC-10760; PGFL; PLGF; PlGF

Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.

Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

placenta growth factor isoform 2; Placenta growth factor; placenta growth factor; placental growth factor, vascular endothelial growth factor-related protein; placental growth factor; N/A

The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include fibroblast growth factor (FGF), platelet derived growth factor (PDGF), vascular endothelial growth factor (VEGF) and placenta growth factor (PlGF). Like VEGF, several PlGF vari- ants have been shown to arise from alternative mRNA splicings. Evidence has suggested VEGF to be an obligatory component in PlGF signaling. While VEGF homodimers and VEGF/PlGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PlGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PlGF. VEGF and PlGF share a common receptor, Flt-1, and may also activate Flk-1/KDR.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.