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- IgM (Immunoglobulin Mu Heavy Chain)
Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438335
Product detailed description
Additional isotype
IgM
Gene name synonims
N/A
Purification method
N/A
Form/Appearance
N/A
Concentration
N/A
Also known as
IgM
Gene name
IGHM
Clonality
Monoclonal
Category
Antibodies
Immunoglobulin isotype
IgG1, kappa
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Clone
DA4-4; same as SA-DA4 or HB57
Other gene names
IGHM; IGHM; MU; VH; AGM1; N/A
Other names
Ig mu chain C region, partial; Ig mu chain C region; N/A; immunoglobulin heavy constant mu; N/A
Tested applications:
ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Species reactivity
Human (Homo sapiens).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Properties
Immunoglobulin M, or IgM for short, is a basic antibody that is produced by B cells. IgM is by far the physically largest antibody in the human circulatory system. It is the first antibody to appear in response to initial exposure to an antigen
Specificity and cross-reactivity
Recognizes a protein of 75kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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