Product short description
Price:
354 EUR
Size:
100ug
Catalog no.:
GEN438388
Product detailed description
Concentration
N/A
Form/Appearance
N/A
Purification method
N/A
Gene name synonims
N/A
Also known as
Actin
Gene name
ACTA2
Clone
SPM332
Clonality
Monoclonal
Category
Antibodies
Immunoglobulin isotype
IgG2a, kappa
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Other gene names
ACTA2; ACTA2; AAT6; ACTSA; MYMY5; ACTSA; ACTVS
Tested applications:
ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)
Storage and shipping
Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
Other names
actin, aortic smooth muscle; Actin, aortic smooth muscle; actin, aortic smooth muscle; alpha-cardiac actin; cell growth-inhibiting gene 46 protein; actin, alpha 2, smooth muscle, aorta; Alpha-actin-2; Cell growth-inhibiting gene 46 protein
Species reactivity
Human (Homo sapiens), Baboon, Monkey, Cow, Pig, Sheep, Goat, Cat, Dog, Rabbit (Oryctolagus cuniculus), Mouse (Mus musculus), Rat (Rattus norvegicus), Guinea pig, Chicken.; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Actin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.