Platelet Derived Growth Factor Receptor, Type B, phosphorylated (Tyr740) (PDGFRb)

603 EUR

100ul

GEN633031

N/A

N/A

5i127

Purified

Antibodies

Monoclonal

Western Blot (WB)

Mnoclonal antibodies

Human (Homo sapiens)

Rabbit (Oryctolagus cuniculus)

Platelet Derived Growth Factor Receptor, Type B

PDGFRB; PDGFRB; JTK12; PDGFR; CD140B; PDGFR1; N/A

PDGFRB; PDGFRB; JTK12; PDGFR; CD140B; PDGFR1; N/A

PDGFRB; PDGFRB; JTK12; PDGFR; CD140B; PDGFR1; N/A

Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM NaCl, 100ug/ml BSA, 50% glycerol.

Human (Homo sapiens), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

platelet-derived growth factor receptor; Beta-type platelet-derived growth factor receptor; beta-type platelet-derived growth factor receptor; PDGF-R-beta; OTTHUMP00000160528; CD140 antigen-like family member B; platelet-derived growth factor receptor, beta polypeptide; CD140 antigen-like family member B

Detects endogenous levels of PDGF receptor b only when phosphorylated at tyrosine 740. The antibody may crossreact with activated PDGF receptor-a. Species Crossreactivity: Human Rat; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.Platelets, also called thrombocytes or cloth cells in blood and are needed to stop bleeding by clumping and clotting the blood the vessels when the an injury occurs. Teh bone marrow will produce the platelets that have no nucleus. Platelates are unique to mammals, the are curved shaped 1900nm to 3100 nm large nucleus free clothing structures.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.