Mouse Anti-CytokeRatin 16 / KeRatin K16

343 EUR

1 mililiter

GEN570103

N/A

N/A

N/A

N/A

N/A

N/A

IgG1

LL025

Antibodies

Monoclonal

Mus musculus

Mnoclonal antibodies

Mouse (Mus musculus)

CytokeRatin 16 / KeRatin K16

Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin), Western Blot (WB)

Each vial contains 1ml of culture supernatant of monoclonal antibody containing 0.09% sodium azide.

Store the antibody at +4 degrees Celsius., or in small aliquots the antibody should be stored at -20 degrees Celsius..

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

KeRatin 16 is specifically found in hyperprolifeRative squamous epithelium such as psoriatic lesions and squamous cell carcinomas, e.g. of the lung. It is expressed in suprabasal keRatinocytes of wounded epidermis, a situation of high cell turnover. LL025 reactivity is negative in, e.g. normal skin, breast and lung tissue and non-invasive breast carcinoma. However, 10% of the invasive breast carcinomas tested were diffusely or focally positive with this antibody.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.