Mouse Anti-CytokeRatin 8+18

343 EUR

1 mililiter

GEN570158

N/A

N/A

IgG2a

NCL-5D3

Antibodies

Monoclonal

Mus musculus

CytokeRatin 8+18

Mnoclonal antibodies

Mouse (Mus musculus)

KRT8; KRT8; K8; KO; CK8; CYK8; K2C8; CARD2; CYK8

KRT8; KRT8; K8; KO; CK8; CYK8; K2C8; CARD2; CYK8

KRT8; KRT8; K8; KO; CK8; CYK8; K2C8; CARD2; CYK8

Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin), Western Blot (WB)

Each vial contains 1 ml of culture supernatant of monoclonal antibody containing 0.09% sodium azide.

Store the antibody at +4 degrees Celsius., or in small aliquots the antibody should be stored at -20 degrees Celsius..

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

cytokeratin 8; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8; CK-8; keratin-8; cytokeratin 8; cytokeratin-8; type-II keratin Kb8; keratin 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

NCL-5D3 recognizes all simple epithelia including glandular epithelia. It does not react with stRatified squamous epithelium. Useful for the differentiation between carcinomas and lymphomas. In Western blot, NCL-5D3 is directed anti the 52.2 kD cytokeRatin 8 (originally reported also to 45 kD cytokeRatin 18; formerly also designated cytokeRatins according to the Moll-Catalogue). Epitope has been mapped to aa 353-367 on alpha helical rod domain of cytokeRatin 8 (see Waseem et al., 2004).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.