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- Mouse Anti-Melanoma Associated Antigen
Product short description
Price:
343 EUR
Size:
1 mililiter
Catalog no.:
GEN570276
Product detailed description
Gene name
N/A
Gene name synonims
N/A
Concentration
N/A
Other gene names
N/A
Purification method
N/A
Immunoglobulin isotype
IgG2b
Clone
NKI-Beteb
Category
Antibodies
Clonality
Monoclonal
Latin name
Mus musculus
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Also known as
Melanoma Associated Antigen
Other names
melanoma-associated antigen; N/A
Tested applications:
Immunohistochemistry (IHC) (frozen), Immunohistochemistry (IHC) (paraffin)
Form/Appearance
Each vial contains 1ml of culture supernatant of monoclonal antibody containing 0.09% sodium azide.
Storage and shipping
Store the antibody at +4 degrees Celsius., or in small aliquots the antibody should be stored at -20 degrees Celsius..
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antigens are peptides or recombinant or native dependent on the production method.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Specificity and cross-reactivity
NKI-Beteb reacts with Melanoma Associated Antigen, a glycoprotein of 100 + 7 kDa. Melanoma associated antigen (MAA) is dispersed in the cytoplasma of melanoma cells, and is more concentRated inside vacuoles and sometimes on the melanosomes. Occasionally the antigen is seen on the cell surface. The antigen is actively shed from living cells. Melanoma Associated Antigen 100 + 7 kDa is present in melanomas, clear cells sarcomas (melanoma of soft tissue), nevocellular nevi, and normal melanocytes. Except for one case of non Hodgkin's lymphoma in which macrophages were positive, the antigen has not been detected with other tumors or tissues observed. The antibody reacts with melanomas, clear cell sarcomas (melanoma of soft tissue), nevocellular nevi, and normal melanocytes. The antibody reacts with melanomas, clear cell sarcomas (melanoma of soft tissue), nevocellular nevi, and normal melanocytes.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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