Product short description
Price:
343 EUR
Size:
1 mililiter
Catalog no.:
GEN570337
Product detailed description
Clone
D33
Purification method
N/A
Concentration
N/A
Immunoglobulin isotype
IgG1
Also known as
Desmin
Category
Antibodies
Clonality
Monoclonal
Latin name
Mus musculus
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Other gene names
DES; DES; CSM1; CSM2; LGMD2R; N/A
Gene name synonims
DES; DES; CSM1; CSM2; LGMD2R; N/A
Gene name
DES; DES; CSM1; CSM2; LGMD2R; N/A
Form/Appearance
Each vial contains 1ml hybridoma culture supernatant
Other names
desmin; Desmin; desmin; mutant desmin p.K241E; intermediate filament protein; desmin; N/A
Tested applications:
Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB)
Storage and shipping
Store the antibody at +4 degrees Celsius., or in small aliquots the antibody should be stored at -20 degrees Celsius..
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Gene
Desmins or DES proteins detect by anti-desmin antibodies and DES ELISA kits. DSM1 and DSM2 play an important role in Desminopathy. Desmin regulated Myofibrilate Myopathy is a protein filament mutation of muscle proteins.
Species reactivity
Human (Homo sapiens), Hamster, Rat (Rattus norvegicus), Chicken; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Specificity and cross-reactivity
The antibody D33 reacts exclusively with desmin, which is expressed in smooth and striated muscle cells and their tumors e.g. rhabdomyosarcoma and leiomyosarcoma in human, hamster, rat and chicken. The antibody does not cross react with vimentin or any of the other intermediate filament proteins.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.