Microphthalmia (MiTF, Homolog of Mouse Microphthalmia, Mi, Microphthalmia-associated Transcription Factor, WS2A)

575 EUR

100ug

GEN600138

N/A

IgG1

8L774

Antibodies

Monoclonal

Mus musculus

Microphthalmia

Western Blot (WB)

Mouse (Mus musculus)

Mitf; Mitf; N/A; N/A

Mitf; Mitf; N/A; N/A

Mitf; Mitf; N/A; N/A

Mnoclonal antibodies

Human (Homo sapiens)

Affinity Purified by immunoaffinity chromatography.

Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.

microphthalmia associated transcription factor; Microphthalmia-associated transcription factor; microphthalmia-associated transcription factor; microphthalmia-associated transcription factor; N/A

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Recognizes human Microphthalmia. Species Crossreactivity: Mouse, rat ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.