Kir, Low Endotoxin (KIR2D, Killer Cell Immunoglobulin (Ig)-like Receptor, CD158a, CD158b, P50.3)

790 EUR

500ug

GEN600318

N/A

cell

IgG1

4j52

Antibodies

Monoclonal

Kir, Low Endotoxin

Mnoclonal antibodies

Mouse (Mus musculus)

Tissue culture supernatant

Affinity Purified by Protein G affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added.

ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)

KIR3DL1; KIR3DL1; KIR; NKB1; NKAT3; NKB1B; CD158E1; KIR3DL1/S1; CD158E; NKAT3; NKB1; NKAT-3

KIR3DL1; KIR3DL1; KIR; NKB1; NKAT3; NKB1B; CD158E1; KIR3DL1/S1; CD158E; NKAT3; NKB1; NKAT-3

KIR3DL1; KIR3DL1; KIR; NKB1; NKAT3; NKB1B; CD158E1; KIR3DL1/S1; CD158E; NKAT3; NKB1; NKAT-3

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze the antibody should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Recognizes KIR2D members of the killer cell immunoglobulin (Ig)-like receptor (KIR) family: CD158a, CD158b and P50.3. Specifically recognizes the long and short forms CD158a and CD158b (KIR2DL, KIR2DS1 and KIR2DS2 respectively) and also p50.3 (KIR2DS4). Reported to have functional activity, activating NK cell cytotoxicity via KIR2DS and inhibiting via KIR2DL forms. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

For cells, cell lines and tissues in culture till half confluency.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

killer cell immunoglobulin-like receptor 3DL1; Killer cell immunoglobulin-like receptor 3DL1; killer cell immunoglobulin-like receptor 3DL1; NKAT-3; NK-receptor; KIR antigen 3DL1; killer Ig receptor; p70 NK receptor CL-2/CL-11; MHC class I NK cell receptor; CD158 antigen-like family member E; p70 killer cell inhibitory receptor; natural killer-associated transcript 3; HLA-BW4-specific inhibitory NK cell receptor; p70 natural killer cell receptor clones CL-2/CL-11; killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1; CD158 antigen-like family member E; HLA-BW4-specific inhibitory NK cell receptor; MHC class I NK cell receptor; Natural killer-associated transcript 3; NKAT-3; p70 natural killer cell receptor clones CL-2/CL-11