SMRT (Silencing Mediator of Retinoic Acid and Thyroid Hormone Receptor)

680 EUR

100ug

GEN600491

N/A

SMRT

IgG1

6D768

thyroid

Purified

Antibodies

Monoclonal

Human (Homo sapiens)

Mnoclonal antibodies

Mouse (Mus musculus)

ncor2; N/A; smrt; N/A

ncor2; N/A; smrt; N/A

ncor2; N/A; smrt; N/A

Store the antibody at -20 degrees Celsius.

Western Blot (WB), Immunohistochemistry (IHC)

Liquid. Purified antibody in PBS containing 1mg/ml BSA and 0.05% sodium azide.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

silencing mediator for retinoid and thyroid hormone receptor; N/A; nuclear receptor corepressor 2; nuclear receptor co-repressor 2; silencing mediator for retinoid and thyroid hormone receptor; silencing mediator of retinoic acid and thyroid hormone receptors; nuclear receptor corepressor 2

Recognizes human SMRT. Detects bands of ~250kDa and ~220kDa by Western blot corresponding to two known isoforms of SMRT.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Hormone releasing factors and releasing hormones are  signaling molecules produced by glands in multicellular organisms. The glands that secrete Luteinizing hormones LHRG and LH, FSH comprise the endocrine signaling system. The term growth hormone releasing hormone GHRH is sometimes extended to include chemicals produced by cells that affect the same cell (autocrine or intracrine signaling) or nearby cells (paracrine signaling). Human recombinant LHRG and GHRH are produced in E. coli or in yeast cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.