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- Cytokeratin 18, Caspase-cleaved
Product short description
Price:
801 EUR
Size:
200 Tests
Catalog no.:
GEN600616
Product detailed description
Concentration
N/A
Clone
6D45
Immunoglobulin isotype
IgG2b
Purification method
Purified
Category
Antibodies
Clonality
Monoclonal
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Source organism
Human (Homo sapiens)
Gene name
KRT18; KRT18; K18; CYK18; CYK18
Gene name synonims
KRT18; KRT18; K18; CYK18; CYK18
Other gene names
KRT18; KRT18; K18; CYK18; CYK18
Also known as
Cytokeratin 18, Caspase-cleaved
Form/Appearance
Supplied as a liquid in PBS, 0.1% BSA, PEG, sucrose, 0.09% sodium azide.
Tested applications:
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
Species reactivity
Bovine, Human (Homo sapiens), Monkey; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Description
Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Other names
cytokeratin 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein; keratin 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Specificity and cross-reactivity
Recognizes the human CK18-Asp396 neo-epitope (M30) of caspase-cleaved CK18. Species Crossreactivity: monkey and bovine. Does not crossreact with intact CK18.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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