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- TLR4/MD-2 Complex (Toll Like Receptor 4/MD-2)
Product short description
Price:
719 EUR
Size:
100ug
Catalog no.:
GEN600997
Product detailed description
Concentration
N/A
Clone
6A641
Immunoglobulin isotype
IgG2a
Category
Antibodies
Clonality
Monoclonal
Also known as
TLR4/MD-2 Complex
Gene name
TLR4; N/A; N/A; N/A
Gene name synonims
TLR4; N/A; N/A; N/A
Other gene names
TLR4; N/A; N/A; N/A
Subcategory
Mnoclonal antibodies
Source organism
Mouse (Mus musculus)
Purification method
Affinity Purified IgG
Host organism
Rat (Rattus norvegicus)
Tested applications:
Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
Form/Appearance
Supplied as a liquid in PBS, containing 0.02% sodium azide and 0.1% BSA.
Other names
toll-like receptor 4; Toll-like receptor 4; toll-like receptor 4; N/A; N/A
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Reacts preferentially, especially in flow cytometry, with mouse TLR4 that is associated with MD-2. Recognizes the mouse TLR4/MD-2 complex and is not useful for detection of TLR4 alone.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store the antibody should be stored at -20 degrees Celsius. or colder. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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