NFATC2 (NFATc2, NF-ATc2, NFATP, NFAT1, T-cell transcription factor NFAT1, Nuclear factor of activated T-cells, cytoplasmic 2)

890 EUR

100ug

GEN602086

N/A

IgG1

6D607

NFATC2

Purified

Antibodies

Monoclonal

cell, cells

Mouse (Mus musculus)

Mnoclonal antibodies

Mouse (Mus musculus)

NFATC2; NFATC2; NFAT1; NFATP; NFAT1; NFATP

NFATC2; NFATC2; NFAT1; NFATP; NFAT1; NFATP

NFATC2; NFATC2; NFAT1; NFATP; NFAT1; NFATP

Supplied as a liquid in PBS, 0.05% sodium azide.

Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Gel Shift Assay (GS/EMSA)

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Recognizes mouse NF-ATc2. Detects bands of ~140kDa (phosphorylated NF-ATc2 in resting immune cells) and ~120kDa (fully-dephosphorylated NF-ATc2 in stimulated cells) by Western blot. Does not cross-react with NF-ATc1. Species Crossreactivity: human and rat.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.

nuclear factor of activated T-cells, cytoplasmic 2 isoform D; Nuclear factor of activated T-cells, cytoplasmic 2; nuclear factor of activated T-cells, cytoplasmic 2; NF-ATc2; OTTHUMP00000031291; OTTHUMP00000031292; NFAT pre-existing subunit; T cell transcription factor NFAT1; T-cell transcription factor NFAT1; NFAT transcription complex, preexisting component; preexisting nuclear factor of activated T-cells 2; nuclear factor of activated T-cells, preexisting component; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; NFAT pre-existing subunit; NF-ATp; T-cell transcription factor NFAT1

For cells, cell lines and tissues in culture till half confluency.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.