Microphthalmia (Transcription Factor, MiTF)

768 EUR

1 mililiter

GEN602190

N/A

IgG1

6A131

Antibodies

Monoclonal

Microphthalmia

Mnoclonal antibodies

Mitf; Mitf; N/A; N/A

Mitf; Mitf; N/A; N/A

Mitf; Mitf; N/A; N/A

Mouse (Mus musculus)

Human (Homo sapiens)

Immunohistochemistry (IHC)

Purified from mouse ascites

Supplied as a liquid in PBS, pH 7.4, and 1% BSA with 0.1% sodium azide

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

microphthalmia associated transcription factor; Microphthalmia-associated transcription factor; microphthalmia-associated transcription factor; microphthalmia-associated transcription factor; N/A

Recognizes both mouse and human MITF.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze the antibody should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.