Ryanodine Receptor

696 EUR

50ug

GEN603319

N/A

IgG2b

2Q263

Antibodies

Monoclonal

Ryanodine Receptor

Mnoclonal antibodies

Mouse (Mus musculus)

Tissue culture supernatant

RYR1; N/A; CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; N/A

RYR1; N/A; CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; N/A

RYR1; N/A; CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; N/A

Supplied as a liquid in PBS, pH 7.5, 0.01% sodium azide.

Highly Purified by ammonium sulfate precipitate followed by DEAE chromatography.

ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Radioimmunoassay (RIA), Gel Shift Assay (GS/EMSA)

Bovine, Canine, Human (Homo sapiens), Mouse (Mus musculus), Porcine, Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

ryanodine receptor; Type 1-like ryanodine receptor; ryanodine receptor 1; ryanodine receptor type1; central core disease of muscle; type 1-like ryanodine receptor; skeletal muscle ryanodine receptor; skeletal muscle calcium release channel; sarcoplasmic reticulum calcium release channel; ryanodine receptor 1 (skeletal); N/A

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Reacts with the C-terminus cytoplasmic domain of ryanodine receptor (500kD), isolated from a variety of cell types (e.g. lymphocytes, macrophages, granulocytes, fibroblasts, epithelial, endothelial cells, skeletal muscle, cardiac muscle and brain tissues). Species Crossreactivity: Human, rat, mouse, canine, porcine and bovine cells/tissue.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.