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- Hypoxia Inducible Factor 1b (HIF-1b, ARNT, Aryl hydrocarbon Receptor Nuclear Translocator)
Product short description
Price:
630 EUR
Size:
100ul
Catalog no.:
GEN603549
Product detailed description
Concentration
N/A
Gene name
N/A
Gene name synonims
N/A
Other gene names
N/A
Clone
3C145
Immunoglobulin isotype
IgG1,k
Category
Antibodies
Clonality
Monoclonal
Tested applications:
Western Blot (WB)
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Source organism
Human (Homo sapiens)
Also known as
Hypoxia Inducible Factor 1b
Other names
hypoxia-inducible factor 1b; N/A
Purification method
Affinity Purified by Protein G affinity chromatography.
Form/Appearance
Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
Species reactivity
Bovine, Ferret, Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Sheep; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes human Hypoxia-inducible factor 1 beta (HIF-1 beta, ARNT) Species crossreactivity: Human, bovine, sheep, mouse, rat and ferret; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze the antibody should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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