LAP2 (Lamina Associated Polypeptide 2, CMD1T, MGC61508, PRO0868, Thymopoietin, TMPO, TP, Thymopoietin Related Peptide Isoform alpha, Thymopoietin Related Peptide Isoforms beta/gamma)

735 EUR

100ul

GEN603629

N/A

N/A

N/A

N/A

LAP2

IgG1

8L565

Antibodies

Monoclonal

Mouse ascites

Mnoclonal antibodies

Mouse (Mus musculus)

Human (Homo sapiens)

Leucine aminopeptidase 2; N/A

15mM Sodium Azide; 0.01M PBS. pH 7.4

Western Blot (WB), Immunohistochemistry (IHC)

Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Species Crossreactivity: Crossreacts with Human. Expected to crossreact with Mouse (100% identity with immunogen), Rat (100% identity with immunogen), Xenopus laevis (90% identity with immunogen) and bovine (88% identity with immunogen) due to sequence homology. Not yet tested in other species.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

The LAP2 (Lamina Associated Polypeptide 2, CMD1T, MGC61508, PRO0868, Thymopoietin, TMPO, TP, Thymopoietin Peptide Isoform alpha, Thymopoietin Peptide Isoforms beta/gamma) is a α- or alpha protein sometimes glycoprotein present in blood.Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.

Thymopoietin I and II are proteins involved in the induction of CD90 in the thymus. The thymopoetin (TMPO) gene encodes three alternatively spliced mRNAs encoding proteins of 75 kDa (alpha), 51 kDa (beta) and 39 kDa (gamma) which are ubiquitously expressed in all cells. The human TMPO gene maps to chromosome band 12q22 and consists of eight exons. TMPO alpha is present diffusely expressed with the cell nucleus while TMPO beta and gamma are localized to the nuclear membrane. TMPO beta is a human homolog of the murine protein LAP2. LAP2 plays a role in the regulation of nuclear architecture by binding lamin B1 and chromosomes. This interaction is regulated by phosphorylation during mitosis. Given the nuclear localization of the three TMPO isoforms, it is unlikely that these proteins play any role in CD90 induction.