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- Ryanodine Receptor 1,2 (RyR)
Product short description
Price:
912 EUR
Size:
100ul
Catalog no.:
GEN603820
Product detailed description
Concentration
N/A
Immunoglobulin isotype
IgG1
Clone
6D748
Source organism
Chicken
Category
Antibodies
Clonality
Monoclonal
Purification method
Ascites Ascites
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Also known as
Ryanodine Receptor 1,2
Form/Appearance
Supplied as a liquid in PBS, 0.05% sodium azide.
Other gene names
RYR1; N/A; CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; N/A
Gene name synonims
RYR1; N/A; CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; N/A
Gene name
RYR1; N/A; CCO; MHS; RYR; MHS1; RYDR; SKRR; RYR-1; N/A
Tested applications:
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
Species reactivity
Bovine, Canine, Chicken, Frog, Human (Homo sapiens), Monkey, Mouse (Mus musculus), Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), Sheep; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
ryanodine receptor 1; Type 1-like ryanodine receptor; ryanodine receptor 1; ryanodine receptor type1; central core disease of muscle; type 1-like ryanodine receptor; skeletal muscle ryanodine receptor; skeletal muscle calcium release channel; sarcoplasmic reticulum calcium release channel; ryanodine receptor 1 (skeletal); N/A
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Specificity and cross-reactivity
Recognizes the alpha, beta and cardiac isoforms of chicken RyR-1 and Ryr-2. Species Crossreactivity: human, mouse, rat, monkey, bovine, sheep, canine, rabbit and amphibian and fish RyR-1 and RyR-2 isoforms. Detects alpha, beta and cardiac isoforms in chicken. Recognizes frog alpha and beta isoforms, the fish alpha isoform, as well as RyR-3 in mouse cells. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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