Integrin, alpha1, beta1 (CD49a, VLA alpha1, Laminin Receptor, Collagen Receptor) (Biotin)

630 EUR

100ug

GEN603859

N/A

N/A

N/A

N/A

N/A

IgG1

6A410

Antibodies

Monoclonal

Biotinylated

Human (Homo sapiens)

Mnoclonal antibodies

Mouse (Mus musculus)

Integrin, alpha1, beta1

ELISA (EL/EIA), Flow Cytometry (FC/FACS)

Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.1% sodium azide. Conjugated to Biotin.

Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )

Affinity Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant.

N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Recognizes human alpha 1 integrin subunit, which forms the VLA-1 heterodimer in association with the beta 1 integrin. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze the antibody should be stored at -20 degrees Celsius.. Aliquots are stable for at least 6 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.