NFkB Repressing Factor (NKRF, ITBA4, NRF)

437 EUR

50ug

GEN603882

N/A

IgG2b

8J130

Antibodies

Monoclonal

Mouse (Mus musculus)

Mnoclonal antibodies

Human (Homo sapiens)

NFkB Repressing Factor

NKRF; NKRF; NRF; ITBA4; ITBA4; NRF

NKRF; NKRF; NRF; ITBA4; ITBA4; NRF

NKRF; NKRF; NRF; ITBA4; ITBA4; NRF

Western Blot (WB), Gel Shift Assay (GS/EMSA)

Affinity Purified by Protein G affinity chromatography.

Supplied as a liquid in PBS, 1% BSA and 0.05% sodium azide.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

NF-kappa-B-repressing factor isoform 2; NF-kappa-B-repressing factor; NF-kappa-B-repressing factor; OTTHUMP00000023906; OTTHUMP00000023907; transcription factor NRF; NFKB repressing factor; Protein ITBA4; Transcription factor NRF

Recognizes human NFkB Repressing Factor.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory