Muscarinic Receptor M4 (Cholinergic Muscarinic Receptor M4, Chrm4)

625 EUR

100ul

GEN603968

N/A

IgG1

2Q146

Purified

Antibodies

Monoclonal

Mouse (Mus musculus)

Human (Homo sapiens)

Mnoclonal antibodies

Muscarinic Receptor M4

CHRM4; CHRM4; HM4; M4R; N/A

CHRM4; CHRM4; HM4; M4R; N/A

CHRM4; CHRM4; HM4; M4R; N/A

Supplied as a liquid in PBS, pH 7.6, 0.1% sodium azide.

Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

muscarinic acetylcholine receptor M4; Muscarinic acetylcholine receptor M4; muscarinic acetylcholine receptor M4; OTTHUMP00000205575; cholinergic receptor, muscarinic 4; N/A

Human (Homo sapiens), Monkey, Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Recognizes M4 muscarinic acetylcholine receptor. It is not reactive with the other subtypes. Species Crossreactivity: rat, mouse and monkey. Reacts weakly with human by Western Blot.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.