Specific Intracellular Adhesion Molecule Grabbing Nonintegrin R1 (SIGN-R1)

1475 EUR

0.25 miligrams

GEN604030

N/A

N/A

N/A

IgM

N/A

N/A

8J189

Antibodies

Monoclonal

Mouse (Mus musculus)

Mnoclonal antibodies

Rat (Rattus norvegicus)

Purified by ammonium sulfate precipitation.

Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide

Specific Intracellular Adhesion Molecule Grabbing Nonintegrin R1

Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the Specific Intracellular Adhesion Molecule Grabbing Nonintegrin R1 (SIGN-R1).Whole adhesion and interacting molecules are  present in lysates used as reference for ELISA quantification of these molecules and their subunits.

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Recognizes mouse SIGN-R1, a C-type lectin that has been identified as a murine homolog of the human CD-SIGN related molecule, L-SIGN. Mouse SIGN-R1 is specifically expressed on marginal zone macrophages in the spleen, medullary and subcapsular sinus macrophages in the lymph nodes, and at lower levels on liver sinusoidal endothelial cells. SIGN-R1 has not been detected on murine dendritic cell populations. Blocks the uptake of neutral polysaccharides by macrophages.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.