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- KLRK1 (Killer Cell Lectin-like Receptor Subfamily K Member 1, CD314, HGNC:18788, D12S2489E, NK Cell Receptor D, NK Lectin-like Receptor, NKLLR, NKG2D Activating NK Receptor, NKG2D Type II Integral Membrane Protein, NKR P2) (PE)
Product short description
Price:
630 EUR
Size:
100 Tests
Catalog no.:
GEN604694
Product detailed description
Concentration
N/A
Tissue
cell
Immunoglobulin isotype
IgG1
Also known as
KLRK1
Clone
10B1393
Category
Antibodies
Clonality
Monoclonal
Subcategory
Mnoclonal antibodies
Source organism
Human (Homo sapiens)
Host organism
Mouse (Mus musculus)
Tested applications:
Flow Cytometry (FC/FACS)
Other gene names
Klrk1; Klrk1; Nkg2d; NKG2-D; D6H12S2489E; Nkg2d
Gene name synonims
Klrk1; Klrk1; Nkg2d; NKG2-D; D6H12S2489E; Nkg2d
Gene name
Klrk1; Klrk1; Nkg2d; NKG2-D; D6H12S2489E; Nkg2d
Purification method
Affinity Purified by Protein G affinity chromatography.
Form/Appearance
Supplied as a lyophilized powder from PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE). Reconstitute with 1ml sterile 40-50% glycerol, ddH2O.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes human KLRK1. Inhibits T cell recognition of MICA a ligand of KLRK1.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Other names
Klrk1; Klrk1 protein; NKG2-D type II integral membrane protein; NK cell receptor D; natural killer cell group 2D; NKG2-D-activating NK receptor; killer cell lectin-like receptor subfamily K, member 1; NKG2-D-activating NK receptor; NK cell receptor D; Killer cell lectin-like receptor subfamily K member 1
Storage and shipping
May be stored at Store the antibody at +4 degrees Celsius. before opening. DO NOT FREEZE! Stable at Store the antibody at +4 degrees Celsius. as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 12 months at Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Description
For cells, cell lines and tissues in culture till half confluency.Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. ,The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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