Urokinase Plasminogen Activator Receptor (uPAR, CD87)

724 EUR

100ul

GEN605397

N/A

9B5

IgG1

Antibodies

Monoclonal

Mouse (Mus musculus)

Mnoclonal antibodies

Human (Homo sapiens)

ELISA (EL/EIA), Western Blot (WB)

Urokinase Plasminogen Activator Receptor

PLAUR; PLAUR; CD87; UPAR; URKR; U-PAR; MO3; UPAR

PLAUR; PLAUR; CD87; UPAR; URKR; U-PAR; MO3; UPAR

PLAUR; PLAUR; CD87; UPAR; URKR; U-PAR; MO3; UPAR

Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.

Affinity Purified by Protein A/G affinity chromatography.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

urokinase plasminogen activator receptor; Urokinase plasminogen activator surface receptor; urokinase plasminogen activator surface receptor; monocyte activation antigen Mo3; u-plasminogen activator receptor form 2; plasminogen activator, urokinase receptor; Monocyte activation antigen Mo3

Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 

Recognizes human uPAR. Reacts with an epitope on domain 1 and differs from that of U2610-04E. Reacts with native uPAR but not with the reduced protein. Inhibits binding to uPAR in solution and on cells. Does not crossreact with murine uPAR, human uPA, human tPA or human PAI-1.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.