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- MBS Monoclonals
- CD91, 515kD (LRP, alpha2MR, Low Density Lipoprotein Receptor-related Protein)
Product short description
Price:
641 EUR
Size:
50ug
Catalog no.:
GEN605784
Product detailed description
Concentration
N/A
Immunoglobulin isotype
IgG1
Clone
5F142
Category
Antibodies
Clonality
Monoclonal
Also known as
CD91, 515kD
Subcategory
Mnoclonal antibodies
Source organism
Human (Homo sapiens)
Host organism
Mouse (Mus musculus)
Other gene names
C4bp; C4bpa; C4bpa; AI195242; C4bp; C4bp
Gene name synonims
C4bp; C4bpa; C4bpa; AI195242; C4bp; C4bp
Gene name
C4bp; C4bpa; C4bpa; AI195242; C4bp; C4bp
Purification method
Affinity Purified by Protein A affinity chromatography.
Tested applications:
Western Blot (WB), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Immunofluorescence (IF)
Other names
C4b-binding protein; C4b-binding protein; C4b-binding protein; complement component 4 binding protein; N/A
Form/Appearance
Supplied as a lyophilized powder from PBS, pH 7.4, 0.5% BSA. Reconstitute with 1ml sterile 40-50% glycerol, ddH2O.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
Lyophilized powder Store the antibody at +4 degrees Celsius for short term storage.. Reconstitute to nominal volume by adding sterile 40-50% glycerol, ddH2O and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Specificity and cross-reactivity
Specifically recognizes the 515kD a-chain of human LRP/a2MR which is expressed in a restricted spectrum of cell types. A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurons and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. Can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD 91). ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description
High and low density proteins are supplied by MBS Monoclonals in volumes of 1. Other densities are possible.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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