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- RUNX3 (Runt-related Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, Acute Myeloid Leukemia Gene 2, AML2, AML-2, Core Binding Factor alpha 3 Subunit, Core Binding Factor Runt Domain alpha Subunit 3, CBF-alpha-3, CBFA3, FLJ34510, MGC16070, Oncogen
Product short description
Price:
437 EUR
Size:
50ug
Catalog no.:
GEN607322
Product detailed description
Concentration
N/A
Immunoglobulin isotype
IgG1
Clone
9j77
Also known as
RUNX3
Virus
leukemia
Category
Antibodies
Clonality
Monoclonal
Tested applications:
Western Blot (WB)
Subcategory
Mnoclonal antibodies
Source organism
Human (Homo sapiens)
Host organism
Mouse (Mus musculus)
Purification method
Affinity Purified by Protein G affinity chromatography.
Form/Appearance
Supplied as a liquid in PBS, pH 7.4, 1% BSA and 0.05% sodium azide.
Other gene names
RUNX3; RUNX3; AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070; AML2; CBFA3; PEBP2A3
Gene name synonims
RUNX3; RUNX3; AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070; AML2; CBFA3; PEBP2A3
Gene name
RUNX3; RUNX3; AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070; AML2; CBFA3; PEBP2A3
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes human RUNX3.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
Other names
runt-related transcription factor 3 isoform 2; Runt-related transcription factor 3; runt-related transcription factor 3; CBF-alpha-3; PEA2 alpha C; PEA2-alpha C; PEBP2 alpha C; PEBP2-alpha C; oncogene AML-2; OTTHUMP00000003370; OTTHUMP00000003371; transcription factor AML2; acute myeloid leukemia gene 2; acute myeloid leukemia 2 protein; core-binding factor subunit alpha-3; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit; core-binding factor, runt domain, alpha subunit 3; polyomavirus enhancer-binding protein 2 alpha C subunit; runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding protein 2 alpha C subunit; PEA2-alpha C; PEBP2-alpha C; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit
Description
The RUNX3 (Runt- Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, Acute Myeloid Leukemia 2, AML2, AML-2, Core Binding Factor alpha 3 Subunit, Core Binding Factor Runt Domain alpha Subunit 3, CBF-alpha-3, CBFA3, FLJ34510, MGC16070, Oncogen is a α- or alpha protein sometimes glycoprotein present in blood.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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