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- RUNX3 (Runt-related Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, AML2, CBFA3, CBF-alpha-3, Core-binding Factor Subunit alpha-3, Oncogene AML-2, PEA2-alpha C, PEBP2A3, PEBP2aC, PEBP2-alpha C, Polyomavirus Enhancer-binding Protein 2 alpha C Sub
Product short description
Price:
757 EUR
Size:
100 Tests
Catalog no.:
GEN609733
Product detailed description
Concentration
N/A
Also known as
RUNX3
Immunoglobulin isotype
IgG2A
Clone
10K25
Virus
leukemia
Category
Antibodies
Clonality
Monoclonal
Subcategory
Mnoclonal antibodies
Source organism
Human (Homo sapiens)
Host organism
Mouse (Mus musculus)
Tested applications:
Flow Cytometry (FC/FACS)
Purification method
Affinity Purified by Protein G affinity chromatography.
Other gene names
RUNX3; RUNX3; AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070; AML2; CBFA3; PEBP2A3
Gene name synonims
RUNX3; RUNX3; AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070; AML2; CBFA3; PEBP2A3
Gene name
RUNX3; RUNX3; AML2; CBFA3; PEBP2aC; FLJ34510; MGC16070; AML2; CBFA3; PEBP2A3
Form/Appearance
Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes human RUNX3.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Storage and shipping
May be stored at Store the antibody at +4 degrees Celsius. before opening. DO NOT FREEZE! Stable at Keep the antibody refrigerated at +4 degrees Celsius. Temperature variations in the range between +1C to +7C are tolerable. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of activity. APC conjugates are sensitive to light.
Other names
runt-related transcription factor 3 isoform 2; Runt-related transcription factor 3; runt-related transcription factor 3; CBF-alpha-3; PEA2 alpha C; PEA2-alpha C; PEBP2 alpha C; PEBP2-alpha C; oncogene AML-2; OTTHUMP00000003370; OTTHUMP00000003371; transcription factor AML2; acute myeloid leukemia gene 2; acute myeloid leukemia 2 protein; core-binding factor subunit alpha-3; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit; core-binding factor, runt domain, alpha subunit 3; polyomavirus enhancer-binding protein 2 alpha C subunit; runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding protein 2 alpha C subunit; PEA2-alpha C; PEBP2-alpha C; SL3-3 enhancer factor 1 alpha C subunit; SL3/AKV core-binding factor alpha C subunit
Description
The RUNX3 (Runt- Transcription Factor 3, Acute Myeloid Leukemia 2 Protein, AML2, CBFA3, CBF-alpha-3, Core-binding Factor Subunit alpha-3, Oncogene AML-2, PEA2-alpha C, PEBP2A3, PEBP2aC, PEBP2-alpha C, Polyomavirus Enhancer-binding Protein 2 alpha C Sub is a α- or alpha protein sometimes glycoprotein present in blood.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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