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- STAT 5, phosphorylated (Signal Transducer and Activator of Transcription 5)
Product short description
Price:
663 EUR
Size:
50ug
Catalog no.:
GEN631781
Product detailed description
Concentration
N/A
Clone
6A188
Also known as
STAT 5
Immunoglobulin isotype
IgG1,k
Category
Antibodies
Clonality
Monoclonal
Subcategory
Mnoclonal antibodies
Source organism
Human (Homo sapiens)
Host organism
Mouse (Mus musculus)
Tested applications:
ELISA (EL/EIA), Western Blot (WB)
Purification method
Affinity Purified by immunoaffinity chromatography
Form/Appearance
Supplied as a liquid in PBS, pH 7.4, containing 0.05% sodium azide.
Species reactivity
Bovine, Human (Homo sapiens), Rat (Rattus norvegicus), Sheep; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other gene names
Stat92E; Stat92E; CG4257; d-STAT; D-stat; D-Stat; D-STAT; D-stat/stat92E; DmelCG4257; DmSTAT; DRODSRC; DSRC; dstat; dSTAT; Dstat; DSTAT; Dstat 92E; dSTAT92E; Dstat92E; dSTAT92E/marelle; l(3)06346; l(3)j6C8; mrl; mrL; mrl stat92E; pSTAT; SD-stat; stat; Stat; STAT; STAT 92E;; MARE; mrL; Stat; d-STAT
Gene name synonims
Stat92E; Stat92E; CG4257; d-STAT; D-stat; D-Stat; D-STAT; D-stat/stat92E; DmelCG4257; DmSTAT; DRODSRC; DSRC; dstat; dSTAT; Dstat; DSTAT; Dstat 92E; dSTAT92E; Dstat92E; dSTAT92E/marelle; l(3)06346; l(3)j6C8; mrl; mrL; mrl stat92E; pSTAT; SD-stat; stat; Stat; STAT; STAT 92E;; MARE; mrL; Stat; d-STAT
Gene name
Stat92E; Stat92E; CG4257; d-STAT; D-stat; D-Stat; D-STAT; D-stat/stat92E; DmelCG4257; DmSTAT; DRODSRC; DSRC; dstat; dSTAT; Dstat; DSTAT; Dstat 92E; dSTAT92E; Dstat92E; dSTAT92E/marelle; l(3)06346; l(3)j6C8; mrl; mrL; mrl stat92E; pSTAT; SD-stat; stat; Stat; STAT; STAT 92E;; MARE; mrL; Stat; d-STAT
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Specificity and cross-reactivity
Recognizes the tyrosine phosphorylated form of STAT5a and STAT5b proteins. It does not cross-react appreciably with the corresponding tyrosine phosphorylated forms of other STAT proteins or with other endogenous phosphotyrosine containing proteins. Species sequence homology: human, bovine, sheep, and rat STAT5 proteins.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Other names
Signal-transducer and activator of transcription protein at 92E, isoform M; Signal transducer and transcription activator; CG4257 gene product from transcript CG4257-RH; CG4257-PB; CG4257-PC; CG4257-PE; CG4257-PF; CG4257-PG; CG4257-PH; CG4257-PI; CG4257-PJ; CG4257-PK; CG4257-PL; CG4257-PM; Signal-transducer and activator of transcription protein; Signal-transducer and activator of transcription protein at 92E; Stat92E-PB; Stat92E-PC; Stat92E-PE; Stat92E-PF; Stat92E-PG; Stat92E-PH; Stat92E-PI; Stat92E-PJ; Stat92E-PK; Stat92E-PL; Stat92E-PM; marelle; signal transducer and activator of transcription; signal transducers and activator of transcription; Signal-transducer and activator of transcription protein at 92E; Protein marelle
Description
STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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