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- TCF3 (Transcription Factor E2-alpha, Class B Basic Helix-loop-helix Protein 21, bHLHb21, Immunoglobulin Enhancer-binding Factor E12/E47, Immunoglobulin Transcription Factor 1, Kappa-E2-binding Factor, Transcription Factor 3, TCF-3, Transcription Factor IT
Product short description
Price:
614 EUR
Size:
100ug
Catalog no.:
GEN633127
Product detailed description
Concentration
N/A
Also known as
TCF3
Immunoglobulin isotype
IgG2B
Clone
10K84
Category
Antibodies
Clonality
Monoclonal
Subcategory
Mnoclonal antibodies
Source organism
Human (Homo sapiens)
Host organism
Rat (Rattus norvegicus)
Tested applications:
ELISA (EL/EIA), Immunohistochemistry (IHC)
Purification method
Affinity Purified by Protein G affinity chromatography.
Other gene names
TCF3; TCF3; E2A; E47; ITF1; VDIR; TCF-3; bHLHb21; BHLHB21; E2A; ITF1; bHLHb21; TCF-3
Gene name synonims
TCF3; TCF3; E2A; E47; ITF1; VDIR; TCF-3; bHLHb21; BHLHB21; E2A; ITF1; bHLHb21; TCF-3
Gene name
TCF3; TCF3; E2A; E47; ITF1; VDIR; TCF-3; bHLHb21; BHLHB21; E2A; ITF1; bHLHb21; TCF-3
Form/Appearance
Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with sterile PBS.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes human TCF-3.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Storage and shipping
Lyophilized powder may be stored the antibody should be stored at -20 degrees Celsius.. Stable for 12 months the antibody should be stored at -20 degrees Celsius.. Reconstitute with PBS. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other names
transcription factor E2-alpha isoform E12; Transcription factor E2-alpha; transcription factor E2-alpha; kappa-E2-binding factor; VDR interacting repressor; transcription factor ITF-1; helix-loop-helix protein HE47; immunoglobulin transcription factor 1; vitamin D receptor-interacting repressor; class B basic helix-loop-helix protein 21; negative vitamin D response element-binding protein; transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47); transcription factor 3; Class B basic helix-loop-helix protein 21; bHLHb21; Immunoglobulin enhancer-binding factor E12/E47; Immunoglobulin transcription factor 1; Kappa-E2-binding factor; Transcription factor 3; TCF-3; Transcription factor ITF-1
Description
The TCF3 (Transcription Factor E2-alpha, Class B Helix-loop-helix Protein 21, bHLHb21, Immunoglobulin Enhancer-binding Factor E12/E47, Immunoglobulin Transcription Factor 1, Kappa-E2-binding Factor, Transcription Factor 3, TCF-3, Transcription Factor IT is a α- or alpha protein sometimes glycoprotein present in blood.Basic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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