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- MBS Monoclonals
- TCR, alpha, beta (T Cell Receptor, T-cell Receptor beta-1 Chain C Region, TRBC1, T-cell Receptor alpha Chain C Region, TRAC, TCRA) (FITC)
Product short description
Price:
707 EUR
Size:
500ug
Catalog no.:
GEN633230
Product detailed description
Gene name
N/A
Gene name synonims
N/A
Other gene names
N/A
Concentration
N/A
Immunoglobulin isotype
IgG
Clone
H57-597
Host organism
Hamster
Category
Antibodies
Clonality
Monoclonal
Tissue
cell, region
Also known as
TCR, alpha, beta
Other names
TCR, partial; N/A
Conjugation
Anti-FITC Antibody
Subcategory
Mnoclonal antibodies
Source organism
Mouse (Mus musculus)
Tested applications:
Flow Cytometry (FC/FACS)
Storage and shipping
Store the antibody at -20 degrees Celsius.
Purification method
Affinity Purified by Protein G affinity chromatography.
Form/Appearance
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Species reactivity
Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Specificity and cross-reactivity
Recognizes the mouse alpha/beta T cell receptor. Does not show any reactivity towards the gamma/delta T cell receptor. This antibody will activate T cells when used in immobilized form (1).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Properties
This MBS Monoclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MBS Monoclonals FITC is highly sensitive to pH extremes.
Description
The TCR, alpha, beta (T Receptor, T- Receptor beta-1 Chain C Region, TRBC1, T- Receptor alpha Chain C Region, TRAC, TCRA) (FITC) is a α- or alpha protein sometimes glycoprotein present in blood.For cells, cell lines and tissues in culture till half confluency.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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