STAT 5b, phosphorylated (Ser133) (Signal Transducer and Activator of Transcription 5b)

663 EUR

500ug

GEN633318

N/A

9A131

IgG1,k

STAT 5b

Antibodies

Monoclonal

ELISA (EL/EIA)

Mnoclonal antibodies

Human (Homo sapiens)

Mouse (Mus musculus)

STAT5B; STAT5B; STAT5; N/A

STAT5B; STAT5B; STAT5; N/A

STAT5B; STAT5B; STAT5; N/A

Affinity Purified by immunoaffinity chromatography.

Supplied as a lyophilized powder from a solution of 0.01M PBS, pH7.0. Reconstitution: Double distillated water is recommended and to adjust the final concentration to 1mg/ml.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

signal transducer and activator of transcription 5B; Signal transducer and activator of transcription 5B; signal transducer and activator of transcription 5B; OTTHUMP00000198374; transcription factor STAT5B; signal transducer and activator of transcription 5B; N/A

Reactive to the immunogen human STAT5b, phosphorylated (pS133) (Signal Transducers and Activators of Transcription 5b), peptide-BSA conjugating and peptide in ELISA.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Lyophilized powder Store the antibody at +4 degrees Celsius for short term storage.. Reconstitute to nominal volume by adding sterile 40-50% glycerol and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Reconstituted product is stable for 24 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.