p53, phosphorylated (Ser392) (Tumor Suppressor Protein, Oncogene Protein)

807 EUR

100ug

GEN633372

p53

N/A

IgG1

tumor

3H2806

Antibodies

Monoclonal

Mnoclonal antibodies

Human (Homo sapiens)

Mouse (Mus musculus)

Store the antibody at -20 degrees Celsius.

TP53; TP53; P53; LFS1; TRP53; FLJ92943; P53

TP53; TP53; P53; LFS1; TRP53; FLJ92943; P53

TP53; TP53; P53; LFS1; TRP53; FLJ92943; P53

Affinity Purified by Protein A affinity chromatography.

Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.

Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

P53; Cellular tumor antigen p53; cellular tumor antigen p53; antigen NY-CO-13; OTTHUMP00000221333; OTTHUMP00000221334; OTTHUMP00000221336; OTTHUMP00000221337; OTTHUMP00000221340; phosphoprotein p53; p53 tumor suppressor; transformation-related protein 53; tumor protein p53; Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53

Recognizes human p53, specifically binding only to p53 phosphorylated at the Ser392 residue. Ser392 phosphorylation of p53 has been shown to occur following DNA damage. Phosphorylation of p53 at this site may be mediated the casein kinase 2 (CK2) and also be other phosphorylation mechanisms. In Immunohistochemistry this antibody generally stains 5-10% of cells labelled with antibodies specific for non-phosphorylated p53.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.