5-Hydroxymethylcytosine (5hmC, 5'OH methyl cytosine)

724 EUR

100ug

GEN644609

N/A

IgG2a,k

AB3/63.3

Antibodies

Monoclonal

Mnoclonal antibodies

Rat (Rattus norvegicus)

5-Hydroxymethylcytosine

hmces; N/A; im:7137789; zgc:165500; N/A

hmces; N/A; im:7137789; zgc:165500; N/A

hmces; N/A; im:7137789; zgc:165500; N/A

Immunocytochemistry (ICC), Gel Shift Assay (GS/EMSA)

Affinity Purified by Protein G affinity chromatography.

Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM NaCl, 0.05% sodium azide.

N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

5-hydroxymethylcytosine (hmC) binding, ES cell-specific; N/A; 5-hydroxymethylcytosine (hmC) binding, ES cell-specific; 5-hydroxymethylcytosine (hmC) binding, ES cell-specific; 5-hydroxymethylcytosine (hmC) binding, ES cell-specific; N/A

Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Detects 5-hydroxymethyl cytosine, but not 5-methylcytosine or unmethylated cytosine. Non-species specific antibody against modified DNA. Expected to detect 5-hydroxymethylcytosine in all species.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms — CH3. In formulas, the group is often abbreviated Me. Such hydrocarbon groups occur in many organic compounds. It is a very stable group in most molecules. While the methyl group is usually part of a larger molecule, it can be found on its own in any of three forms anion, cation or radical. The anion has eight valence electrons, the radical seven and the cation six. All three forms are highly reactive and rarely observed,