STAT3, phosphorylated (Tyr705) (Signal Transducer and Activator of Transcription 3, Acute-phase Response Factor, APRF) (Alexa Fluor 647)

658 EUR

500ul

GEN609313

IgG

N/A

7H65

STAT3

Antibodies

Monoclonal

Mnoclonal antibodies

Mouse (Mus musculus)

Alexa Fluor,ALEXA FLUOR 647

Rabbit (Oryctolagus cuniculus)

STAT3; STAT3; APRF; HIES; APRF

STAT3; STAT3; APRF; HIES; APRF

STAT3; STAT3; APRF; HIES; APRF

Purified prior to conjugation.

ELISA (EL/EIA), Flow Cytometry (FC/FACS)

Store the antibody at +4 degrees Celsius. Protect from light. Do not freeze.

Supplied in PBS, pH 7.2, less than 0.1% sodium azide, 2 mg/ml BSA. Conjugated to Alexa Fluor® 647 under optimal conditions with an F/P ratio of 2-5.

Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

signal transducer and activator of transcription 3 isoform 1; Signal transducer and activator of transcription 3; signal transducer and activator of transcription 3; DNA-binding protein APRF; acute-phase response factor; signal transducer and activator of transcription 3 (acute-phase response factor); Acute-phase response factor

Detects endogenous levels of Stat3 only when phosphorylated at Tyr705. Does not crossreact with phospho-EGFR or with corresponding phospho-tyrosines of other Stat proteins. Species Crossreactivity: Mouse.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

For facs or microscopy Alexa 1 conjugate.Alexa Fluor 633 is a practical alternative to APC as well as Cy5. MBS Monoclonals made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the STAT3, phosphorylated (Tyr705) (Signal Transducer Activator of Transcription 3, Acute-phase Response Factor, APRF) ( ) exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy.

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.