Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T cell Specific Transcription Factor 1 alpha, TCF1 alpha)

520 EUR

50ug

GEN600490

N/A

cell

IgG1

6D538

Antibodies

Monoclonal

Mouse (Mus musculus)

Mnoclonal antibodies

Lymphoid Enhancer Factor 1

Western Blot (WB), Immunocytochemistry (ICC)

Highly Purified by size exclusion chromatography.

LEF1; LEF1; LEF-1; TCF10; TCF7L3; TCF1ALPHA; LEF-1; TCF1-alpha

LEF1; LEF1; LEF-1; TCF10; TCF7L3; TCF1ALPHA; LEF-1; TCF1-alpha

LEF1; LEF1; LEF-1; TCF10; TCF7L3; TCF1ALPHA; LEF-1; TCF1-alpha

Supplied as a liquid in PBS, 0.1% sodium azide, PEG and sucrose, before the addiition of glycerol to 40%.

Human (Homo sapiens), Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

lymphoid enhancer-binding factor 1 isoform 1; Lymphoid enhancer-binding factor 1; lymphoid enhancer-binding factor 1; TCF1-alpha; T cell-specific transcription factor 1-alpha; lymphoid enhancer-binding factor 1; T cell-specific transcription factor 1-alpha

Recognizes human and mouse LEF. Does not cross-react with T cell factor 3 (TCF3) or T cell factor 4 (TCF4). Detects a band of ~68kDa by Western blot.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Store the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.

The Lymphoid Enhancer Factor 1 (LEF1, Lymphoid Enhancer-binding Factor 1, DKFZp586H0919, HGNC:6551, T Specific Transcription Factor 1 alpha, TCF1 alpha) is a α- or alpha protein sometimes glycoprotein present in blood.For cells, cell lines and tissues in culture till half confluency.Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.