MOUSE Anti-CANINE HEARTWORM:Biotin Antibody

741 EUR

0.25 miligrams

GEN210474

N/A

N/A

N/A

N/A

N/A

IgG1

HW2-83

anticorps

Antibodies

Monoclonal

ELISA (EIA)

Mus musculus

Biotinylated

CANINE HEARTWORM

Mnoclonal antibodies

Mouse (Mus musculus)

IgG concentration 1.0mg/ml

Biotin (Purified IgG conjugated to Biotin - liquid)

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

InvertebRat (Rattus norvegicus)es; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.

CANINE HEARTWORM This item recognises both male and female ether extracted parasite antigen of canine heartworm. _x000D__x000D_Canine heartworm infection, caused by the filarial nematode Dirofilaria immitis, is an insidious and potentially fatal condition transmitted by mosquitoes, which primarily affects the heart and lungs of dogs, but may also affect other species including cats, foxes, sea-lions, ferrets and humans. _x000D__x000D_Canine heartworm disease, resulting ultimately in damage to the pulmonary vasculature system, is largely attributed to the immunological response of the host to the presence of the adult parasites, and in many cases their microscopic offspring (microfilaria) which circulate in the bloodstream, but growing evidence suggests the involvement of further factors/mediators.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.