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- MOUSE Anti-HUMAN APOLIPOPROTEIN B Antibody
Product short description
Price:
636 EUR
Size:
1000ug
Catalog no.:
GEN211466
Product detailed description
Purification method
N/A
Immunoglobulin isotype
IgG1
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Latin name
Mus musculus
Clone
F2C9 (APOB-001)
Also known as
APOLIPOPROTEIN B
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Concentration
Ig concentration 1.0 mg/ml
Form/Appearance
Purified (Purified IgG - liquid)
Tested applications:
RadioImmunoassay (RIA), ELISA (EIA)
Other gene names
APOB; APOB; FLDB; LDLCQ4; Apo B-100; Apo B-48
Gene name synonims
APOB; APOB; FLDB; LDLCQ4; Apo B-100; Apo B-48
Gene name
APOB; APOB; FLDB; LDLCQ4; Apo B-100; Apo B-48
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Other names
apolipoprotein B-100; Apolipoprotein B-100; apolipoprotein B-100; apoB-48; apoB-100; apo B-100; mutant Apo B 100; apolipoprotein B48; apolipoprotein B (including Ag(x) antigen); N/A
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
Test
MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Specificity and cross-reactivity
APOLIPOPROTEIN B This item is specific for human Apolipoprotein B (ApoB), a large secretory protein with a molecular weight of 550kDa that plays a central role in lipoprotein metabolism. ApoB exists in the plasma in 2 main isoforms, ApoB100 and ApoB48. ApoB100 is synthesised in the liver, and is the major apolipoprotein of very low density, intermediate density and low density lipoproteins (LDL), and is absolutely required for their formation. ApoB100 acts as a ligand for LDL receptors in various cells throughout the body, allowing cells to internalise LDL and absorb cholesterol. ApoB48 is expressed in the intestine and is present on chylomicrons and their remnants, and lacks the C-terminal LDL-receptor binding region of ApoB100. Elevated plasma concentrations of ApoB containing lipoproteins are key risk factors for the development of atherosclerosis.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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