Product short description
Price:
486 EUR
Size:
100ug
Catalog no.:
GEN212272
Product detailed description
Gene name synonims
N/A
Purification method
N/A
Also known as
MDM2
Gene name
MDM2
Immunoglobulin isotype
IgG1
Clone
SMP14
French translation
anticorps
Clonality
Monoclonal
Category
Antibodies
Latin name
Mus musculus
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Concentration
IgG concentration 1.0 mg/ml
Form/Appearance
Purified (Purified IgG - liquid)
Other gene names
MDM2; MDM2; HDMX; hdm2; ACTFS; Hdm2
Tested applications:
Immunohistology - Paraffin (IHC), Immunohistology - Resin (IHC), Immunohistology - Frozen (IHC), Immunoprecipitation (IP)
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term. the antibody should be stored undiluted. Storage in frost free freezers is not recommended. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
Specificity and cross-reactivity
MDM2 This item recognises the 90kD MDM2 protein, which forms a complex with p53 leading to p53 inhibition. MDM2 also acts to stimulate cell proliferation via its induction of transcription factors such as E2F1 and DPI. MDM2 is over expressed in a range of human malignancies, including soft tissue sarcomas, breast cancer and bladder cancer.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Other names
E3 ubiquitin-protein ligase Mdm2 isoform MDM2; E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase Mdm2; oncoprotein Mdm2; MDM2 variant FB28; MDM2 variant FB30; HDM2 transcript variant MYO-1; HDM2 transcript variant MYO-4; HDM2 transcript variant MYO-18; HDM2 transcript variant MYO-20; HDM2 transcript variant MYO-24; HDM2 transcript variant MYO-25; HDM2 transcript variant MYO-26; HDM2 transcript variant MYO-32; Mdm2, p53 E3 ubiquitin protein ligase homolog; double minute 2, human homolog of; p53-binding protein; Mdm2, transformed 3T3 cell double minute 2, p53 binding protein; MDM2 oncogene, E3 ubiquitin protein ligase; Double minute 2 protein; Hdm2; Oncoprotein Mdm2; p53-binding protein Mdm2