RAT ANTI MOUSE CD180 Antibody

879 EUR

0.25 miligrams

GEN212524

N/A

N/A

CD180

CD180

IgG2a

RP/14

anticorps

Monoclonal

Antibodies

Mnoclonal antibodies

Rat (Rattus norvegicus)

IgG concentration 0.5 mg/ml

Mus musculus,Rattus norvegicus

Purified (Purified IgG - liquid)

Cd180; Cd180; Ly78; RP105; F630107B15; Ly78; Rp105; Ly-78

Flow Cytometry (FACS), Functional Assay (FA), Immunoprecipitation (IP), Western Blot (WB)

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

CD180 antigen; CD180 antigen; CD180 antigen; ly-78; lymphocyte antigen 78; radioprotective 105 kDa protein; CD180 antigen; Lymphocyte antigen 78; Ly-78; Radioprotective 105 kDa protein

Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.This is against a protein of mus musculus directed antibody.

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term. the antibody should be stored undiluted. Storage in frost-free freezers is not recommended. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.

CD180 Clone RP/14 recognizes mouse CD180 (RP105) a 105kD type 1 transmembrane protein, which belongs to the toll-like receptor family. CD180 is primarily expressed in mature peripheral B cells and is thought to play a role in the innate immune response to bacterial lipopolysaccharide, through co-operation with MD-1 and TLR4. _x000D__x000D_Cross linking of CD180 with clone RP/14 has been reported to induce resistance against irradiation induced apoptosis, B-cell proliferation and up-regulation of a co-stimulatory molecule B7.2 Removal of sodium azide is recommended prior to use in functional studies.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.