MOUSE Anti-HUMAN TYROSINASE RELATED PROTEIN 1 Antibody

652 EUR

1 mililiter

GEN212869

N/A

N/A

Ta99

IgG2a

anticorps

Antibodies

Monoclonal

Mus musculus

Mouse (Mus musculus)

Mnoclonal antibodies

TYROSINASE RELATED PROTEIN 1

Immunohistology - Frozen (IHC)

Concentrate (Concentrated Tissue Culture Supernatant - liquid)

TYRP1; TYRP1; TRP; CAS2; CATB; GP75; OCA3; TRP1; TYRP; b-PROTEIN; CAS2; TYRP; TYRRP; DHICA oxidase; TRP; TRP-1; TRP1

TYRP1; TYRP1; TRP; CAS2; CATB; GP75; OCA3; TRP1; TYRP; b-PROTEIN; CAS2; TYRP; TYRRP; DHICA oxidase; TRP; TRP-1; TRP1

TYRP1; TYRP1; TRP; CAS2; CATB; GP75; OCA3; TRP1; TYRP; b-PROTEIN; CAS2; TYRP; TYRRP; DHICA oxidase; TRP; TRP-1; TRP1

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

5,6-dihydroxyindole-2-carboxylic acid oxidase; 5,6-dihydroxyindole-2-carboxylic acid oxidase; 5,6-dihydroxyindole-2-carboxylic acid oxidase; catalase B; DHICA oxidase; glycoprotein 75; melanoma antigen gp75; tyrosinase-related protein 1; Catalase B; Glycoprotein 75; Melanoma antigen gp75; Tyrosinase-related protein 1

Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.

MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

TYROSINASE RELATED PROTEIN 1 This item detects Tyrosinase-related protein-1 (TRP-1), a 75kDa melanocyte-specific gene product involved in eumelanin synthesis which is present on the melanosomal membrane of melanoma, normal melanocytes and nevi. Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintanence of melanosome ultrastructure and affects melanocyte proliferation and cell death. _x000D__x000D_Defects in TRP-1 affect pigmentation in melanosomes, and have been shown to cause two diseases dependent on skin colour; rufous oculocutaneous albinism (ROCA) occurs predominantly in southern African blacks and oculocutaneous albinism type III (OCA-III/3) a form of albinism with only moderate reduction of pigment. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.