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- MOUSE Anti-HUMAN TROPONIN COMPLEX (CARDIAC) Antibody
Product short description
Price:
475 EUR
Size:
200ug
Catalog no.:
GEN214519
Product detailed description
Purification method
N/A
Clone
20C6
Immunoglobulin isotype
IgG2b
French translation
anticorps
Category
Antibodies
Clonality
Monoclonal
Tested applications:
ELISA (EIA)
Latin name
Mus musculus
Also known as
TROPONIN COMPLEX
Host organism
Mouse (Mus musculus)
Subcategory
Mnoclonal antibodies
Form/Appearance
Purified (Purified IgG - liquid)
Concentration
IgG concentration 1 miligram per 1 mililiter
Other gene names
TNNC1; TNNC1; TNC; TN-C; TNNC; CMD1Z; CMH13; TNNC; TN-C
Gene name synonims
TNNC1; TNNC1; TNC; TN-C; TNNC; CMD1Z; CMH13; TNNC; TN-C
Gene name
TNNC1; TNNC1; TNC; TN-C; TNNC; CMD1Z; CMH13; TNNC; TN-C
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names
troponin C, slow skeletal and cardiac muscles; Troponin C, slow skeletal and cardiac muscles; troponin C, slow skeletal and cardiac muscles; troponin C1, slow; cardiac troponin C; slow twitch skeletal/cardiac muscle troponin C; troponin C type 1 (slow); N/A
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
Test
MBS Monoclonals supplies antibodies that are for research of human proteins.Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Specificity and cross-reactivity
TROPONIN COMPLEX This item recognises human troponin, a complex of three proteins integral to muscle contraction. The three-unit troponin complex (Troponin I, T and C), bound to tropomyosin, is located on the actin filament of skeletal and cardiac muscle. Troponin T binds to tropomyosin to form the troponin-tropomyosin complex. Troponin C binds calcium ions to produce a conformational change in Troponin I. Troponin I binds to the actin in thin myofilaments to hold the troponin-tropomyosin complex in place. When calcium binds to troponin, a conformation change is forced in troponin and tropomyosin, moving both proteins away from the myosin binding sites on the actin filaments. Thus, myosin can bind to actin and muscle contraction occurs. _x000D__x000D_This item recognises the native troponin complex. It does not cross-react with any of the individual components Troponin I, T or C.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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