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- MBS Monoclonals
- MOUSE Anti-NEWCASTLE DISEASE VIRUS Antibody
Product short description
Price:
531 EUR
Size:
200ug
Catalog no.:
GEN214574
Product detailed description
Gene name
N/A
Gene name synonims
N/A
Other gene names
N/A
Purification method
N/A
Other names
N/A
Clone
8H2
Immunoglobulin isotype
IgG2a
French translation
anticorps
Virus
newcastle
Category
Antibodies
Clonality
Monoclonal
Tested applications:
ELISA (EIA)
Latin name
Mus musculus
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Also known as
NEWCASTLE DISEASE VIRUS
Concentration
IgG concentration 1.0mg/ml
Form/Appearance
Purified (Purified IgG- liquid)
Properties
If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Species reactivity
Viral; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Storage and shipping
Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
Specificity and cross-reactivity
NEWCASTLE DISEASE VIRUS This item recognises the hemagglutinin-neuraminidase (HN) protein of Newcastle disease virus (NDV). Newcastle disease is a highly contagious disease affecting wild and domestic birds. Symptoms of the disease vary greatly, depending on the strain of virus and the species, age and health of the bird. Virulence of the disease can also vary greatly, with some strains causing very high mortality rates. In humans, NDV can cause mild influenza-like symptoms. The HN protein of the virus is a type II membrane glycoprotein on virion and infected cell surfaces. It binds to sialic acid-containing cellular receptors and promotes activity of the viral fusion protein, thereby allowing the virus to penetrate the cell. It also removes sialic acids from progeny virus particles to prevent viral self-agglutination. _x000D__x000D_Newcastle disease virus is tumor selective and oncolytic. It has shown promise for selective growth in and killing of a variety of tumor cells._x000D__x000D_; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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