MOUSE Anti-PLASMODIUM VIVAX CSP Antibody

531 EUR

200ug

GEN214578

N/A

N/A

N/A

N/A

N/A

IgG1

PVC-1

anticorps

Antibodies

Monoclonal

Mus musculus

Mnoclonal antibodies

Mouse (Mus musculus)

PLASMODIUM VIVAX CSP

IgG concentration 500ug/1000ul

ELISA (EIA), Western Blot (WB)

Purified (Purified IgG - liquid)

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.

Protozoan; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.

PLASMODIUM VIVAX CSP This item recognises the circumsporozoite protein (CSP) of Plasmodium vivax. Outside sub-Saharan Africa, where P. falciparum infection is most common, P. vivax is the most common cause of malaria infection. While not as deadly as P. falciparum, it does negatively affect human health. Malaria infection is initiated when an infected Anopheles mosquito injects sporozoites into a person's blood during a blood meal. The sporozoites migrate to and infect hepatocytes where they multiply asexually. The CSP is the major surface protein of sporozoites and form a dense coat on the parasite's surface. The CSP is involved in the motility of the sporozoite and the invasion of target cells. It is also required for sporozoite development in the mosquito. The protein has been extensively studied as a vaccine candidate. Vaccination with irradiated sporozoites has been shown to protect against malarial parasites with the sera of protected individuals recognising CSP.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.