MOUSE Anti-YERSINIA PESTIS V ANTIGEN Antibody

531 EUR

200ug

GEN214585

N/A

IgG1

Va13

anticorps

Antibodies

Monoclonal

Mus musculus

Mnoclonal antibodies

Mouse (Mus musculus)

lcrV; lcrV; N/A; icrV

lcrV; lcrV; N/A; icrV

lcrV; lcrV; N/A; icrV

YERSINIA PESTIS V ANTIGEN

IgG concentration 1.0mg/ml

ELISA (EIA), Western Blot (WB)

Purified (Purified IgG - liquid)

secreted effector protein; Virulence-associated V antigen; secreted effector protein; N/A; Low calcium response locus protein V

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Bacterial; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antigens are peptides or recombinant or native dependent on the production method.

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

Store the antibody at +4 degrees Celsius for short-term storage and at -20 degrees Celsius for long-term.Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.

YERSINIA PESTIS V ANTIGEN This item recognises the V antigen of Yersinia pestis (also known as LcrV), a 327-residue soluble protein. Yersinia pestis is a Gram-negative bacillus belonging to the family Enterobacteriaceae. Infection in humans can take the form of bubonic, pneumonic and septicemic plague amongst other less common forms. All three forms have been known for very high mortalitly rates during several epidemics across the world, possibly including the Black Death that ravaged Europe from 1347-1353. Although such large epidemics have not been seen since the Great Plague of London in 1665-1666, the disease still exists and there is concern as to its use as a biological weapon. _x000D__x000D_The V antigen has many complex functions. It mediates the delivery of toxins into host cell, can stimulate production of interleukin-10 (an immunosuppressive cytokine) and it can inhibit chemotaxis of polymorphonuclear neutrophils. Antibodies against LcrV protect against the plague._x000D__x000D_; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.